Variceal Bleeding in Patients with Initation of Sofosbuvir and Ribavirin – Case Reports

Authors

  • Sadiq Memon Department of Gastroenterology, Asian Institute of Medical Sciences, Hyderabad, Pakistan.
  • Madiha Zaki Department of Gastroenterology, Indus Medical College Hospital, Tando Muhammad Khan, Pakistan.
  • Shahzad Ali Jiskani Department of Pathology, Indus Medical College Hospital, Tando Muhammad Khan, Pakistan.

Keywords:

Variceal bleeding, Sofosdbuvir, Ribavirin, Heptitis C, Nucleoside analogue, Antiviral

Abstract

Abstract: Sofosbuvir is an oral nucleoside analogue and potent inhibitor of the Hepatitis C virus (HCV) RNA polymerase that is used in combination with other antiviral agents to treat chronic Hepatitis C Nevertheless, and for unknown reasons, successful antiviral therapy of Hepatitis C with Sofosbuvir and other direct acting agents in patients with cirrhosis is occasionally complicated by hepatic decompensation. Here we describe 2 case report of upper gi bleed at initial days of treatment with Sofosbuvir and Ribavirin.

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Published

2021-07-26

How to Cite

1.
Memon S, Zaki M, Jiskani SA. Variceal Bleeding in Patients with Initation of Sofosbuvir and Ribavirin – Case Reports. Nat J Health Sci [Internet]. 2021Jul.26 [cited 2021Sep.18];5(4):175-6. Available from: https://ojs.njhsciences.com/index.php/njhs/article/view/185

Issue

Section

Case Report