Therapy Related Acute Lymphoblastic Leukemia (t-ALL): Case Report and Literature Review

Authors

  • Asma Ameen Department of Adult Clinical Hematology, National Institute of Blood Disease & Bone Marrow Transplantation, Karachi, Pakistan.
  • Nida Anwar Department of Adult Clinical Hematology, National Institute of Blood Disease & Bone Marrow Transplantation, Karachi, Pakistan.
  • Tahir Sultan Shamsi Department of Adult Clinical Hematology, National Institute of Blood Disease & Bone Marrow Transplantation, Karachi, Pakistan.

Keywords:

Carboplatin, Ovarian cancer, Secondary malignancy, Platinum based chemotherapy, Radiotherapy

Abstract

Abstract: Therapy related Acute Lymphoblastic Leukemia (t-ALL) is a rare secondary malignancy. It occurs in patients who are exposed to chemotherapy and/or radiotherapy for primary malignancy. We are reporting here a case of a thirty five years old female patient who was referred to us for fever, malaise and bleeding from gums. She had a history of ovarian carcinoma for which she took carboplatin and other chemotherapeutic agents. Extensive workup was done which was consistent with the diagnosis of Precursor-B cell Acute Lymphoblastic Leukemia. In the context of previous history of exposure to carboplatin, she was diagnosed as a case of therapy related Acute Lymphoblastic Leukemia secondary to carboplatin.

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Published

2020-12-22

How to Cite

1.
Ameen A, Anwar N, Shamsi TS. Therapy Related Acute Lymphoblastic Leukemia (t-ALL): Case Report and Literature Review. Nat J Health Sci [Internet]. 2020Dec.22 [cited 2022Oct.1];4(2):85-6. Available from: https://ojs.njhsciences.com/index.php/njhs/article/view/53

Issue

Section

Case Report

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