Substantiation of Multinational Association for Supportive Care in Cancer (MASCC) Score in Risk Assessment of Febrile Neutropenic Patients in Hematological Disorders: A Regional Study from Pakistan

Authors

  • Qurratul Ain Rizvi Department of Clinical Hematology & BMT, National Institute of Blood Disease & Bone Marrow Transplantation, Karachi, Pakistan.
  • Aisha Jamal Department of Clinical Hematology & BMT, National Institute of Blood Disease & Bone Marrow Transplantation, Karachi, Pakistan.
  • Naveena Fatima Department of Research & Development, National Institute of Blood Disease & Bone Marrow Transplantation, Karachi, Pakistan.
  • Munira Borhany Department of Clinical Hematology & BMT, National Institute of Blood Disease & Bone Marrow Transplantation, Karachi, Pakistan.
  • Uzma Zaidi Department of Clinical Hematology & BMT, National Institute of Blood Disease & Bone Marrow Transplantation, Karachi, Pakistan.
  • Tahir Sultan Shamsi Department of Clinical Hematology & BMT, National Institute of Blood Disease & Bone Marrow Transplantation, Karachi, Pakistan.

Keywords:

MASCC, Febrile neutropenia, Leukemia, Hematological disorders, Cytotoxic chemotherapy

Abstract

Abstract: Background: The incidence of neutropenia in hematological malignancies comprises of huge burden of febrile neutropenia. Multinational Association of Supportive Care in Cancer (MASCC) risk index score is the most widely used model for forecast of complications.

Objective: The aim of this study was to determine diagnostic accuracy of MASCC scoring system in febrile neutropenia patients suffering from hematological disorders.

Materials & Methods: Patients suffering from hematological disorders and presenting with febrile neutropenia were stratified into low and high risk groups according to MASSC score. The standard score range from 0 to 26 points; score of more than or equals to 21 were considered to be low risk and score of less than 21 was high-risk category. As an in-patient at National Institute of Blood Disease & Bone Marrow Transplantation, they were followed over the course of illness for development of any serious medical condition until resolution of febrile neutropenia.

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Published

2021-03-30

How to Cite

1.
Rizvi QA, Jamal A, Fatima N, Borhany M, Zaidi U, Shamsi TS. Substantiation of Multinational Association for Supportive Care in Cancer (MASCC) Score in Risk Assessment of Febrile Neutropenic Patients in Hematological Disorders: A Regional Study from Pakistan. Nat J Health Sci [Internet]. 2021Mar.30 [cited 2021May16];5(3):99-103. Available from: https://ojs.njhsciences.com/index.php/njhs/article/view/169

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Section

Research Article

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