Experience from Cancer Registry of a Developing Country Regarding Quality of Care and Non-Compliance among Osteosarcoma Patients

Authors

Badaruddin Sahito Department of Orthopedic and Surgery, Dow University of Health Sciences, Karachi, Pakistan.
Sheikh Muhammad Ebad Ali Department of Orthopedic and Surgery, Dow University of Health Sciences, Karachi, Pakistan.
Mustafa Saleem Department of UGME, Dow University of Health Sciences, Karachi, Pakistan.
Noor Muhammad Soomro Department of Oncology, Dr. Ruth KM Pfau Civil Hospital Karachi, Pakistan.
Muhammad Soughat Katto Department of Orthopedic and Surgery, Dr. Ruth KM Pfau Civil Hospital Karachi, Pakistan.
Asif Jatoi Department of Orthopedic and Surgery, Dr. Ruth KM Pfau Civil Hospital Karachi, Pakistan.

Osteosarcoma, Bone tumors, Appraisal, Cancers, Chemotherapy, Surgery

Abstract: In this study, we evaluated the level of care given by our institution and to assess the non-compliance along with predictor for

non-compliance among osteosarcoma patients.

Materials and Methods: The included participants were proven for osteosarcoma after biopsy between January 2014 to December 2020.

Records were searched from Departmental Cancer Registry for details regarding treatment plans and follow-ups. The data of outcomes were

compared with the standard guidelines. Patients who did not attend follow-ups, surgery or chemotherapy were termed as non-compliant. The

patients or their next of kins were inquired about the factors behind non-compliance.

Results: 46 participants with 34 (74.9%) males and 12 (26.1%) females and a mean age of 19.7± 9.7 years were included. The prescribed

treatment plan was followed by 11 (23.91%) patients. Neoadjuvant and adjuvant chemotherapy were taken by 18 (39.13%) and 10 (21.74%)

candidates, respectively. Surgery was performed in 22(44.9%). The patients who did not received chemotherapy was attributed to affordability

(P=0.008) and patients’ or next to kins’ choices (P=0.02) while age (P=0.039), patients’ consent not given (78.3%; P=0.05), and stage II

(52.2%; P=0.048) were predictors of surgical non-compliance.

Conclusion: We conclude that the care deferred significantly from the guidelines regarding surgery and chemotherapy. Age, affordability, late

stage, and personal choices are the significant predictors for non-compliance for chemotherapy and surgery.