The Role of Hemogram Parameters in Predicting Sentinel Lymph Node Metastasis in Breast Cancer

Authors

  • Bahri Ozer Abant Izzet Baysal University Hospital, Department of General Surgery, Bolu, Turkey.
  • Adil Koyuncu Haseki Training and Research Hospital, Department of General Surgery, ?stanbul, Turkey.
  • Songul Peltek Ozer Abant ?zzet Baysal Training and Research Hospital, Department of Pathology, Bolu, Turkey.
  • Oguz Catal Abant Izzet Baysal University Hospital, Department of General Surgery, Bolu, Turkey.
  • Mustafa Sit Abant Izzet Baysal University Hospital, Department of General Surgery, Bolu, Turkey.

Keywords:

Breast cancer, Sentinel lymph node biopsy, Hemogram, Inflammation, Tumor, Auxiliary metastasis

Abstract

Abstract: Background: Breast cancer remains the second most common cancer in the world after lung cancer. Breast cancer rate in Turkey was 40-50 / 100.000 in the west, and was 20 / 100.000 in the east.

Objective: In our study, we aimed to investigate the prediction of hemogram parameters in showing sentinel lymph node metastasis.

Materials & Methods: Patients undergoing sentinel lymph node biopsy (SLNB) with the diagnosis of breast cancer between January 2015 and August 2019 in General Surgery Department of Abant Izzet Baysal University were retrospectively analyzed in present descriptive study. The patients were divided into two groups, SLNB positive and negative. The measured hemogram parameters were compared between these two groups. Analysis of the data was held with a statistical software (SPSS 18.0 for Windows, IBM Inc., Chicago, IL, USA).


Results: A total of 93 patients were included in the study. The average age of SLNB positive and negative patients were 55 (30-81) years 59 (35-88) years respectively. In detecting SLNB positivity, sensitivities and specificities of Tumor diameter> 0.9 cm were 72% sensitivity, 56% specificity, of CRP> 0.65 mg/dL were 76% sensitivity, 51% specificity, of RMR> 1.85 were 72% sensitivity, 46% specificity, of RDW> 15.45% were 75% sensitivity,% 42 specificity, of PLR> 106.5 were 72% sensitivity, 56% specificity.


Conclusion: Since auxiliary metastasis is one of the most important points for the prognosis of breast cancer, we suggest PLR, RDW, RMR could serve as prognostic factors in determining lymph node metastasis along with CRP and tumor size in breast cancer.

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Published

2023-03-21

How to Cite

1.
Ozer B, Koyuncu A, Ozer SP, Catal O, Sit M. The Role of Hemogram Parameters in Predicting Sentinel Lymph Node Metastasis in Breast Cancer. Nat J Health Sci [Internet]. 2023Mar.21 [cited 2024Feb.21];8(1):3-6. Available from: https://ojs.njhsciences.com/index.php/njhs/article/view/325

Issue

Section

Research Article