Platelet Rich Plasma Effects on Diabetic Foot Ulcers - A Review


  • Shamail Zia Department of Pathology, Jinnah Sindh Medical University, Karachi, Pakistan.
  • Abdul Salam Department of Medicine, Allama Iqbal Medical College, Lahore, Pakistan.
  • Sanam Nusrat Department of Surgery, Liaquat University of Medical and Health Sciences, Jamshoro, Pakistan
  • Muhammad Hamza Khan Department of Medicine, Shaikh Khalifa bin Zayed Al Nahyan Medical College, Lahore, Pakistan.
  • Venkata Anirudh Chunchu Department of Medicine, Avalon University School of Medicine, Willemsta, Curacao.
  • Hassan Nawaz Department of Medicine, Nishtar Medical University, Multan, Pakistan.
  • Danial Hassan Department of Healthcare Profession, Ministry of Public Health Qatar, Doha, Qatar.
  • Tatheer Zehra Department of Pediatrics, Allied Hospital, Faislabad, Pakistan.
  • Fazail Zia Department of Pathology, Noor E Zia Consultant Clinics, Karachi, Pakistan.
  • Farozaan Shamail Department of Pathology, Noor E Zia Consultant Clinics, Karachi, Pakistan.


Platelet rich plasma, Platelet growth factors, Autologous cellular therapy, Diabetic foot ulcer, Osteoarthritis, Inflammation


Abstract: Utilizing platelet rich plasma, one of the newest autologous cellular therapies, as an adjuvant therapy in a regenerative medicine management, can be very beneficial. Patients with complications like osteoarthritis, spinal disorders and musculoskeletal problems still facing global lacking in the area of tissue repair strategies. Along with this another major complication associated is with diabetic patients - the development of diabetic foot ulcers that predisposes to limb amputation. To advance the healing process and prevent the patients from progressing towards amputations. Besides many other approaches used. Platelet Rich Plasma (PRP) therapy is attaining momentum, which is composed of platelet growth factors that assist the wound healing cascade – inflammation, proliferation and remodeling. It may occur because of provision of vital growth factors necessary for healing. Currently, variety of PRP formulations have been assessed. The article intends to evaluate the PRP effectiveness for managing diabetic ulcers.




How to Cite

Zia S, Salam A, Nusrat S, Khan MH, Chunchu VA, Nawaz H, Hassan D, Zehra T, Zia F, Shamail F. Platelet Rich Plasma Effects on Diabetic Foot Ulcers - A Review. Nat J Health Sci [Internet]. 2023Mar.21 [cited 2024May29];8(1):28-36. Available from:



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