Rare Transformation of Chronic Myeloid Leukemia into Acute Lymphoblastic Leukemia in a 14-Year Old Patient

Authors

  • Javera Tariq Department of Pathology, Pakistan Institute of Medical Science (PIMS), Islamabad, Pakistan
  • Sundas Ali Department of Pathology, Pakistan Institute of Medical Science (PIMS), Islamabad, Pakistan.
  • Shahzad Ali Jiskani Department of Pathology, Pakistan Institute of Medical Science (PIMS), Islamabad, Pakistan.
  • Rabiah Asghar Department of Pathology, Pakistan Institute of Medical Science (PIMS), Islamabad, Pakistan

Keywords:

Chronic myeloid leukemia, Acute lymphoblastic leukemia, Pediatric, Transformation, Rare

Abstract

Abstract: Chronic myeloid leukemia is a myeloproliferative neoplasm. It is a common disease of elderly, rarely affecting pediatric, adolescent or young adults. The median age of presentation is 65 years. The incidence is 1?2 cases per 100,000 adults. Tyrosine kinase inhibitors (TKIs) are highly successful and have good remission rates in the CML treatment; though multiple factors are associated with failure of treatment. We present a patient of 14 years old male who was diagnosed as CML. He was seven months into TKI therapy, transformed into B-Lineage acute lymphoblastic leukemia.

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Published

2020-11-04

How to Cite

1.
Tariq J, Ali S, Jiskani SA, Asghar R. Rare Transformation of Chronic Myeloid Leukemia into Acute Lymphoblastic Leukemia in a 14-Year Old Patient. Nat J Health Sci [Internet]. 2020Nov.4 [cited 2024Apr.25];5(2):86-8. Available from: https://ojs.njhsciences.com/index.php/njhs/article/view/12

Issue

Vol. 5 No. 2 (2020)

Section

Case Report

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