Drug Induced Pure White Cell Aplasia: A Case Report and Review of Literature

Authors

  • Aisha Jamal Department of Adult Clinical Haematology, National Institute of Blood Diseases and Bone Marrow Transplantation, Karachi, Pakistan.
  • Uzma Zaidi Department of Adult Clinical Haematology, National Institute of Blood Diseases and Bone Marrow Transplantation, Karachi, Pakistan.
  • Jawad Hasan Kazmi Department of Diagnostic Haematology, National Institute of Blood Diseases and Bone Marrow Transplantation, Karachi, Pakistan.
  • Munira Borhany Department of Adult Clinical Haematology, National Institute of Blood Diseases and Bone Marrow Transplantation, Karachi, Pakistan.
  • Qurratulain Rizvi Department of Adult Clinical Haematology, National Institute of Blood Diseases and Bone Marrow Transplantation, Karachi, Pakistan.
  • Tahir Shamsi Department of Adult Clinical Haematology, National Institute of Blood Diseases and Bone Marrow Transplantation, Karachi, Pakistan.

Keywords:

Agranulocytosis, Drug induced pure white cell aplasia, Febrile neutropenia

Abstract

Abstract: Pure White Cell Aplasia (PWCA) is an extremely rare haematological entity. Various causes have been implicated in its pathogenesis. We are reporting here a case of a sixty seven years old female, referred to us with the concern of febrile neutropenia and extensive oral candidiasis. Workup for secondary causes of agranulocytosis was negative. Bone marrow findings were consistent with PWCA, and in the presence of convincing previous history of amodiaquine intake, she was diagnosed as drug (amodiaquine) induced PWCA.

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Published

2021-01-01

How to Cite

1.
Jamal A, Zaidi U, Kazmi JH, Borhany M, Rizvi Q, Shamsi T. Drug Induced Pure White Cell Aplasia: A Case Report and Review of Literature. Nat J Health Sci [Internet]. 2021Jan.1 [cited 2023Jun.9];2(2):88-91. Available from: https://ojs.njhsciences.com/index.php/njhs/article/view/136

Issue

Vol. 2 No. 2 (2017)

Section

Case Report

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