Acquired Trisomy 21 - A Unique Cytogenetic Finding in T-Cell Acute Lymphoblastic Leukemia

Authors

  • Qurratulain Rizvi Department of Clinical Haematology National Institute of Blood Disease & Bone Marrow Transplantation, Karachi, Pakistan.
  • Aisha Jamal Department of Clinical Haematology National Institute of Blood Diseases and Bone Marrow Transplantation, Karachi, Pakistan.
  • Jawad Hassan Department of Molecular Cytogenetics, National Institute of Blood Diseases and Bone Marrow Transplantation, Karachi, Pakistan.
  • Tahir Shamsi Department of Clinical Haematology National Institute of Blood Disease & Bone Marrow Transplantation, Karachi, Pakistan.

Keywords:

Acute lymphoblastic leukemia, Acquired trisomy 21, Cytogenetics, Karyotyping, Lymphadenopathy, T-cell ALL

Abstract

Abstract: Acute lymphoblastic leukemia (ALL), is a lymphoid neoplasm arising from lymphoid progenitors, broadly classified according to lineage into B-cell and T-cell ALL in which T-cell ALL constitutes a small proportion. We are reporting here a case of young female who was diagnosed as T-cell ALL using flow cytometry with acquired trisomy 21, identified on conventional cytogenetics, as a unique finding in this case.

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Published

2020-12-30

How to Cite

1.
Rizvi Q, Jamal A, Hassan J, Shamsi T. Acquired Trisomy 21 - A Unique Cytogenetic Finding in T-Cell Acute Lymphoblastic Leukemia. Nat J Health Sci [Internet]. 2020Dec.30 [cited 2024Apr.19];2(3):135-7. Available from: https://ojs.njhsciences.com/index.php/njhs/article/view/126

Issue

Vol. 2 No. 3 (2017)

Section

Case Report